High resolution small?scale inorganic scintillator detector: HDR brachytherapy application

Purpose Brachytherapy (BT) deals with high gradient internal dose irradiation made up of a complex system where the source is placed nearby tumor to destroy cancerous cells. A primary concern clinical safety in BT quality assurance ensure best matches between delivered and prescribed doses targeting small volume tumors sparing surrounding healthy tissues. Hence, purpose this study evaluate performance point size inorganic scintillator detector (ISD) terms rate brachytherapy (HDR-BT) treatment. Methods prototype verification has been developed based on scintillating dosimetry measure while using an 192Ir source. The associated measured photons/s employing highly sensitive photon counter (design data: 20 photons/s). Dose measurement was performed as function source-to-detector distance according TG43U1 recommendations. Overall measurements were carried out inside water phantoms keeping ISD along needle; minimum 0.1 cm maintained each point. planned dwell times accurately from difference two adjacent transit. performances also evaluated linearity, energy dependency, scintillation stability, signal-to-noise ratio (SNR), signal-to-background (SBR). Finally, comparison presented results obtained TG43 reference dataset. Results detection efficiency verified by measuring at different positions. Measurements demonstrated that perfectly linear behavior (R2 = 1) shows SNR (>35) SBR (>36) values even lowest investigated around 10 Standard deviation (1?) remains within 0.03% signal magnitude, less than 0.01% STEM monitored distance. Stability 0.54% achieved, afterglow stays 1% total all irradiations. Excellent symmetrical regarding position observed radiation planes. TG-43 dataset corrected agreed simulation data 1.2% 1.3%, valid for greater 0.25 cm. Conclusion proposed anticipated could be promoted validate further investigations. It allows appropriate time estimation during tracking suitable spatial resolution both (high gradient) far (low position.